Nitric Oxide
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Nitric Oxide

Nitric oxide dilates blood vessels, which facilitates irrigation to the muscles (and all organs in general). This optimizes the nutrients supply where they are needed the most, which enhances muscle growth, strength, and endurance. In HSNstore, we have supplements that stimulate the nitric oxide production, or blends of creatine and stimulants.

Generally, most athletes, whether professional or amateur, aim to improve muscle efficiency and to increase vascularization for the following purposes: 1. Increasing the nutrients and oxygen supply to the muscles, and 2. Promoting the elimination of lactic acid (one of the main causes of muscle fatigue).

These two objectives are very important both for athletes who are looking for a greater muscle development, and for those whose are more focused on overcoming their personal records by improving their speed or strength.

This is the reason why there are many athletes that choose to buy nitric oxide stimulators.

Nitric oxide, also called nitrogen monoxide (NO), is a gas that is endogenously produced in very small amounts in our bodies by the L-arginine amino acid. One of the most outstanding functions of NO is its ability to promote the dilation of blood vessels.

This dilation allows more blood to reach the muscle cells.

This means that the muscles will receive more oxygen and nutrients, apart from accelerating the elimination of waste substances.

All this results in an improved performance, increased strength, improved recovery, as well as more muscle mass development.

Table of contents

    1. What are nitric oxide stimulating supplements or vasodilating products?
      1. L-arginine and L-citrulline to increase nitric oxide
    2. Other properties/benefits of nitric oxide
    3. How to use nitric oxide stimulating supplements
    4. Side effects of NO stimulators

What are nitric oxide stimulating supplements or vasodilating products?

They are supplements which include ingredients that are capable of activating the mechanisms that favor NO stimulation, which increases vascularization.

The two ingredients that are used to encourage vasodilation are l-arginine and l-citrulline.

L-arginine is a non-essential amino acid (our bodies can synthesise it) and it can be found in many proteins that are present in our daily diet. Once it is absorbed by the digestive tract, arginine travels through the blood to the tissues or organs that require it.

L-arginine promotes the nitric oxide synthesis once it is internalized within the cells through the nitric oxide synthase ecytoplasmic enzyme (NO synthase).

L-arginine and L-citrulline to increase nitric oxide

New pre-workout products with l-arginine are beginning to add citrulline malate as well, since this ingredient has the ability to endogenously increase arginine levels in blood plasma.

In fact, some studies show that consuming l-citrulline increases arginine levels without consuming arginine directly.

Other properties/benefits of nitric oxide

Increasing NO levels within the body has also other beneficial properties:

  • It helps to fight against infectious organisms, specially bacteria.
  • It has an anti-inflammatory effect.
  • It promotes the vasodilation of the circulatory system. This property can be quite useful for people suffering from hypertension or heart problems.
  • NO also has blood thinning effects, helping to prevent the formation of clots that cause heart attacks.
  • This substance is a great companion for memory and cognitive function in the long-term, due to the fact that it increases irrigation to the brain and it acts as a neurotransmitter.
  • It promotes angiogenesis, which is the creation of new blood vessels that will supply a higher percentage of nutrients and oxygen to the muscles, which in turn will accelerate the removal of lactate and improve performance.
  • It causes an increase in the number of mitochondria (mitochondrial biogenesis), which helps to improve the use of fatty acids by the skeletal muscle. Its increase also generates a greater quantity of mitochondrial enzymes, which are vital to increase the ATP production.
  • It promotes muscle regeneration by accelerating recovery processes after physical activity, thanks to its ability to encourage cell division.
  • It also promotes muscle hypertrophy.
  • It helps to protect the integrity of muscle fibres during exercise.
  • We also must not forget its benefits for improving sexual intercourse, because it affects the same metabolic pathway that viagra, causing a similar effect, although to a lesser extent. It is very beneficial for people that suffer from erectile dysfunction.

How to use nitric oxide stimulating supplements

Supplementation with L-arginine and L-citrulline increases the nitric oxide production. However, nitric oxide cannot be stored in the body, which means that these amino acids have to be consumed daily and immediately before exercise.

We should keep in mind that, since it is a molecule that is synthesised by the organism, we should encourage that it generates its own nitric oxide. Otherwise, the endogenous nitric oxide production may be reduced.

Our organism is a machine that produces only what it needs. This is why, as long as there is enough NO available, it will not need to synthesize it.

This is why it is advisable to change supplements from time to time. For example, use nitric oxide stimulators for two or three months, then take a break for two or three months before using a different supplement. Nitric Oxide enhancers are products that should be used with caution and awareness of their effects.

Side effects of NO stimulators

People who suffer from hypotension (low blood pressure) should avoid the consumption of these products, since their vasodilating effect causes a lowering of blood pressure. Using nitric oxide stimulators accelerates aging, since they are substances which release large amounts of free radicals.

It is advisable to combine these products with antioxidants, since it will mitigate the effects of free radicals.

Using these supplements can hinder digestion. When we eat, the blood flow is focused on the stomach, which is vital for the assimilation of nutrients.

However, if we consume nitric oxide stimulating products, the blood is gathered in the muscle tissues, which is the reason it can cause digestive problems. To avoid this issue, we should not eat food at least two hours before consuming nitric oxide and training.

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